:Synthesis of 2-Amino-4,6-dimethoxypyrimidine(ADM)论文

:Synthesis of 2-Amino-4,6-dimethoxypyrimidine(ADM)论文

本文主要研究内容

作者(2019)在《Synthesis of 2-Amino-4,6-dimethoxypyrimidine(ADM)》一文中研究指出:Using malononitrile as the raw material, a novel synthesis route of 2-amino-4,6-dimethoxypyrimidine(ADM) was put forward, in order to solve the instability in first step reaction of industrial synthesis. The influence of reactant ratio, temperature and time on product quality and yield was explored. The results showed that ADM was successfully prepared through acetyl chloride route, the yield was higher than that of industrial production process, and the process stability was good, with the product purity over 99%. Therefore, the new synthesis route is suitable for industrial production.

Abstract

Using malononitrile as the raw material, a novel synthesis route of 2-amino-4,6-dimethoxypyrimidine(ADM) was put forward, in order to solve the instability in first step reaction of industrial synthesis. The influence of reactant ratio, temperature and time on product quality and yield was explored. The results showed that ADM was successfully prepared through acetyl chloride route, the yield was higher than that of industrial production process, and the process stability was good, with the product purity over 99%. Therefore, the new synthesis route is suitable for industrial production.

论文参考文献

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