本文主要研究内容
作者（2019）在《Chiral iminophosphorane catalyzed asymmetric Henry reaction of α,β-alkynyl ketoesters》一文中研究指出：α,β-Alkynyl ketoesters were introduced to the enantioselective Henry reaction(nitroaldol condensation)with nitromethane catalyzed by tartaric acid derived chiral iminophosphoranes. As such, a variety of optically active β-nitro-substituted tertiary alcohols bearing alkyne moieties were obtained in good to excellent yields(42%–99%) and moderate to good level of enantiomeric excess(up to 87% ee).
Abstract
α,β-Alkynyl ketoesters were introduced to the enantioselective Henry reaction(nitroaldol condensation)with nitromethane catalyzed by tartaric acid derived chiral iminophosphoranes. As such, a variety of optically active β-nitro-substituted tertiary alcohols bearing alkyne moieties were obtained in good to excellent yields(42%–99%) and moderate to good level of enantiomeric excess(up to 87% ee).
论文参考文献
[1].Copper-catalyzed synthesis of 1,2-disubstituted benzimidazoles from imidoyl chlorides[J]. Hui Yu~*,Mei Shu Zhang,Li Ren Cui Department of Chemistry,Tongji University,Shanghai 200092,China. Chinese Chemical Letters.2012(05)[2].Copper-catalyzed 1,3-dipolar cycloaddition of methyleneindolinones and N,N’-cyclic azomethine imines[J]. Di Zhang,Da-Ming Zhang,Guang-Yang Xu,Jiang-Tao Sun. Chinese Chemical Letters.2015(03)[3].Rhodium catalyzed asymmetric Pauson-Khand reaction using SDP ligands[J]. FAN Baomin1, LI Shen2, XIE Jianhua2, WANG, Lixin2, TU Yongqiang1 & ZHOU Qilin2 1. State Key Laboratory of Applied Organic Chemistry,Lanzhou University,Lanzhou 730000,China; 2. State Key Laboratory of Elemento-organic Chemistry,Nankai University,Tianjin 300071, China. Science in China(Series B:Chemistry).2006(01)[4].Recent advances in the iron-catalyzed cycloaddition reactions[J]. WANG ChunXiang & WAN BoShun Dalian Institute of Chemical Physics,Chinese Academy of Sciences,Dalian 116023,China. Chinese Science Bulletin.2012(19)[5].Recent progress in transition metal catalyzed cross coupling of nitroarenes[J]. Lifen Peng,Zhifang Hu,Zilong Tang,Yinchun Jiao,Xinhua Xu. Chinese Chemical Letters.2019(08)[6].Advances in theoretical study on transition-metal-catalyzed C-H activation[J]. Yuan-Ye Jiang,Xiaoping Man,Siwei Bi. Science China(Chemistry).2016(11)[7].Gold-catalyzed oxazoles synthesis and their relevant antiproliferative activities[J]. Chao Wu,Zhi-Wu Liang,Ying-Ying Xu,Wei-Min He,Jian-Nan Xiang. Chinese Chemical Letters.2013(12)[8].A Computational Study on the Mechanism for the K2CO3-catalyzed Reaction of Carbon Dioxide and 1-Chlo-2-propanol[J]. 张福兰,万邦江,黄辉胜. 结构化学.2012(01)[9].Benzylation of arenes and heteroarenes catalyzed by HfCl4/HfO2[J]. Cheng Yi Zhang,Xin Qin Gao~*,Jiang Hua Zhang,Xiao Jun Peng State Key Laboratory of Fine Chemicals,Dalian University of Technology,Dalian 116012,China. Chinese Chemical Letters.2009(08)[10].The Studies of Rhodium-catalyzed Ring Opening Reaction of N-Boc-azabenzonorbornadiene with Heteroatom Nucleophiles[J]. Er Chang LIU, Ding Qiao YANG, Ying Feng HAN, Jian Xia DONG School of Chemistry and Environment, South China Normal University, Guangzhou 510006. Chinese Chemical Letters.2006(06)
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：Chiral iminophosphorane catalyzed asymmetric Henry reaction of α,β-alkynyl ketoesters论文
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