导读:本文包含了视动震颤论文开题报告文献综述及选题提纲参考文献，主要关键词:前庭功能,视动性眼球震颤,单侧,非对称
视动震颤论文文献综述
Lopez,C,Borel,L,Magnan,J,Lacour,M.,张磊[1]（2006）在《单侧前庭功能丧失后的扭转视动性眼球震颤的非对称功能及代偿作用》一文中研究指出The aim of this study was to analyse torsional optokinetic nystagmus (tOKN) in 17 patients with Menière’s disease before and after (1 week, 1 month and 3 months)-a curative unilateral vestibular neurotomy (UVN). The tOKN was investigated during optokinetic stimulations around the line of sight directed towards either the lesioned or the healthy side, at various constant angular velocities. Dynamic properties of tOKN and static ocular cyclotorsion were analysed using videonystagmography. Patients’performances were compared with those of 10 healthy subjects. The results indicate that, in the acute stage after UVN, patients exhibited drastic impairment of tOKN velocity that depended on the direction of stimulation: tOKN velocity increased for ipsilesional stimulations and decreased for contralesional stimulations. These changes were responsible for a dramatic tOKN asymmetry, with ipsilesional directional preponderance of torsional slow-phase eye velocity. The changes were associated with static ocular cyclotorsion towards the operated side. Despite progressive compensation of tOKN deficits over time, tOKN velocity still differed from that recorded preoperatively, and tOKN asymmetry remained uncompensated 3 months after UVN. A static ocular cyclotorsion remained up to 3 months after lesion. These results are the first description of tOKN deficits and recovery after unilateral vestibular loss. They show that vestibular cues contribute to gaze stabilization during optokinetic stimulation around the line of sight. They also strongly suggest that tOKN impairment could be part of the longterm asymmetrical functions reported after unilateral loss of vestibular functions.(本文来源于《世界核心医学期刊文摘.眼科学分册》期刊2006年03期）
Garbutt,S,,Riley,D,E[2]（2005）在《进行性核上性麻痹患者视动性眼球震颤异常》一文中研究指出Objectives: To measure vertical and horizontal responses to optokinetic (OK) s timulation and investigate directional abnormalities of quick phases in progress ive supranuclear palsy (PSP). Methods: Saccades and OK nystagmus were studied in six PSP patients, five with Parkinsons disease (PD), and 10 controls. The OK stimulus subtended 72°horizontally, 60°vertically, consisted of black and whit e stripes, and moved at 10-50°/s. Results: All PSP patients showed slowed volu ntary vertical saccades and nystagmus quick phases compared with PD or controls. Small, paired, horizontal saccadic intrusions (SWJ) were more frequent and larg er in PSP during fixation. Vertical saccades were transiently faster at the time of SWJ and horizontal saccades in PSP. During vertical OK nystagmus, small quic k phases were often combined with horizontal SWJ in all subjects; in PSP the vec tor was closer to horizontal. Vertical OK slow phase gain was reduced in PSP but , in most PD patients, was similar to normals. The average position of gaze shif ted in the direction of vertical OK stimulus in PSP patients with preserved slow phase responses but impaired quick phases. Conclusions: Vertical OK responses i n PSP show impaired slow phase responses, and quick phases that are slowed and c ombined with SWJ to produce an oblique vector. SWJ facilitate vertical saccades and quick phases in PSP, but it is unclear whether this is an adaptive process o r a result of the disease. A large OK stimulus is useful to induce responses tha t can be quantitatively analysed in patients with limited voluntary range of ver tical gaze.(本文来源于《世界核心医学期刊文摘(神经病学分册)》期刊2005年02期）
Garbutt,S,,Riley,D,E[3]（2005）在《进行性核上性麻痹所致视动性眼球震颤的异常表现》一文中研究指出Objectives: To measure vertical and horizontal responses to optokinetic (OK) s timulation and investigate directional abnormalities of quick phases in progress ive supranuclear palsy (PSP). Methods: Saccades and OK nystagmus were studied in six PSP patients, five with Parkinson's disease (PD), and 10 controls. The OK stimulus subtended 72°horizontally, 60°vertically, consisted of black and whit e stripes, and moved at 10-50°/s. Results: All PSP patients showed slowed volu ntary vertical saccades and nystagmus quick phases compared with PD or controls. Small, paired, horizontal saccadic intrusions (SWJ) were more frequent and larg er in PSP during fixation. Vertical saccades were transiently faster at the time of SWJ and horizontal saccades in PSP. During vertical OK nystagmus, small quic k phases were often combined with horizontal SWJ in all subjects; in PSP the vec tor was closer to horizontal. Vertical OK slow phase gain was reduced in PSP but , in most PD patients, was similar to normals. The average position of gaze shif ted in the direction of vertical OK stimulus in PSP patients with preserved slow phase responses but impaired quick phases. Conclusions: Vertical OK responses i n PSP show impaired slow phase responses, and quick phases that are slowed and c ombined with SWJ to produce an oblique vector. SWJ facilitate vertical saccades and quick phases in PSP, but it is unclear whether this is an adaptive process o r a result of the disease. A large OK stimulus is useful to induce responses tha t can be quantitatively analysed in patients with limited voluntary range of ver tical gaze.(本文来源于《世界核心医学期刊文摘.眼科学分册》期刊2005年02期）
杨东生,孙复川[4]（1998）在《经直接与间接通路的视动震颤(OKN)眼动反应》一文中研究指出采用鼻向及颞向运动光栅图形刺激猫的半侧视网膜，以探讨鼻侧半视网膜至视束核（NOT）的视动震颤（OKN）直接通路及颞侧半视网膜经皮层至NOT的间接通路对OKN眼动反应的神经控制特性。实验结果显示：高速度刺激的闭环OKN反应及开环OKN反应均对鼻向运动刺激有明显的方向选择性；半侧视网膜刺激时，鼻侧半视网膜的鼻向OKN增益明显高于颞侧半视网膜的鼻向增益，说明猫的OKN眼动反应以跟踪鼻向运动为主，并且这种对鼻向运动刺激的选择性主要来源于鼻侧半视网膜，亦即来源于OKN直接通路；颞侧半视网膜的鼻、颞向眼动增益均明显低于鼻侧半视网膜的鼻向眼动增益，说明猫的OKN系统的间接通路在OKN眼动控制中起辅助作用，并可能主要对颞向OKN眼动起作用从而与双眼视觉功能相关。(本文来源于《生理学报》期刊1998年03期）
韦敏,曹洋,杨东生,孙复川[5]（1998）在《家兔视动震颤(OKN)眼动反应的方向特性》一文中研究指出采用两维方向上运动的光栅作为刺激并以电磁感应眼动测量方法对家兔ＯＫＮ方向特性进行研究。结果表明：水平单一方向运动的图形刺激时，只有鼻向刺激引起ＯＫＮ反应，且ＯＫＮ反应的慢相方向接近于刺激方向，说明水平刺激时，家兔ＯＫＮ反应方向与刺激方向基本一致；其它方向上运动图形刺激时，家兔ＯＫＮ反应方向并没有随刺激方向的改变作相应变化，而基本集中在叁个方向：水平鼻向、垂直向上及垂直向下附近，表明家兔ＯＫＮ的反应方向随不同刺激方向呈非线性的变化特性。(本文来源于《生物物理学报》期刊1998年01期）
曹洋,孙复川[6]（1997）在《复合运动条纹刺激下的视动震颤(OKN)眼动反应》一文中研究指出研究视动震颤（optokineticnystagmus，OKN）眼动系统在同时包含两个二维运动的复合运动条纹（movingcompoundgratings）刺激下的反应特性，并探讨两种子条纹（componentgrating）运动方向的夹角和运动速度的影响。实验结果发现，在一定参数范围内，复合运动条纹引起了双重交替OKN反应，即OKN交替地跟踪合成运动（coherence）和分别运动（transparency）；在跟踪分别运动中，又是交替地跟踪两种子条纹的运动。实验结果还发现，随着两种子条纹运动方向的夹角减小、速度减小，OKN反应跟踪合成运动的时间增加；其中夹角的影响是决定性的。(本文来源于《生理学报》期刊1997年06期）
杨东生[7]（1997）在《视动震颤(Optokinetic Nystagmus)与双眼视功能》一文中研究指出视动震颤（ＯＫＮ）反应与双眼视功能密切相关：１．双眼视功能异常者ＯＫＮ反应以方向性不对称为特点，其机制可能是ＯＫＮ传导通路上视皮层双眼细胞发育异常。２．ＯＫＮ反应的双眼交替与双眼竞争可能受同一神经机制的控制。３．动态随机点立体图刺激及双眼融合参与下的ＯＫＮ反应，是判断双眼视功能的有效方法。４．开环ＯＫＮ方法由于消除了负反馈作用的影响并可对不同部位视网膜刺激，故有较好的应用前景。(本文来源于《眼科研究》期刊1997年01期）
杨东生,吴冰,孙复川,李欢[8]（1996）在《正常及异常双眼视觉的视动震颤（OKN）反应特性研究》一文中研究指出为探讨不同双眼视觉状态下ＯＫＮ反应的特性，对正常人和不同类型的双眼视觉异常者的单眼鼻向及颞向ＯＫＮ反应进行了研究。实验发现：单眼视觉抑制者表现出鼻向与颞向ＯＫＮ反应不对称特性；两眼皆因视剥夺造成双眼视觉异常者主要以ＯＫＮ眼动增益降低为特点；双眼视觉正常者鼻、颞向ＯＫＮ反应是对称的。结果表明：单眼ＯＫＮ眼动反应的不对称特性及增益改变对探讨双眼视觉异常机制有重要意义，为视皮层双眼细胞异常导致单眼ＯＫＮ不对称的假设提供了支持性证据，并对弱视早期诊断及其分类有重要价值。(本文来源于《生物物理学报》期刊1996年04期）
韦敏,孙复川,邵殿华[9]（1995）在《运动图形刺激时家兔的视动震颤反应》一文中研究指出旨在用实验方法研究家兔的视动震颤（ＯＫＮ）眼动特点以及单侧前庭迷路损伤对ＯＫＮ的影响，结果表明：单眼刺激时，家兔的ＯＫＮ反应存在着从颞侧到鼻侧方向的方向优势；恒定速度刺激时，刺激开始后，家兔的ＯＫＮ眼动跟踪速度具有从小到大最后趋于稳态的建立过程，刺激；消失后，存在眼动速度由大到小直到消失的视动后震颤（ＯＫＡＮ）反应，这两个过程反映了ＯＫＮ系统中可能存在速度存储税制及其对ＯＫＮ眼动的控制作用；单侧前庭迷路的损伤虽然不影响家兔ＯＫＮ反应的方向优势，但对刺激各侧眼所引起的ＯＫＮ反应均产生了影响，而且刺激受损侧与未受损侧眼所得到的ＯＫＡＮ反应差异较明显，这一结果提示我们家兔两眼ＯＫＮ速度的存储器可能不在同一部位。(本文来源于《生物物理学报》期刊1995年04期）
韦敏,孙复川[10]（1992）在《不同运动图象同时刺激左右眼时的交替视动震颤(OKN)现象》一文中研究指出采用了同时对左右眼分别以不同的运动图象刺激的实验方法,来测量及分析其OKN眼动反应,探索在OKN反映中两眼之间的输入关系以及眼动控制机制。实验结果发现在两眼的刺激图象不一致时,眼动反应为交替的OKN反应,即中枢神经系统根据各眼的刺激速度,交替地控制产生OKN眼动反应。本文还从闭环控制上讨论了视网膜上速度误差信号的作用。(本文来源于《生物物理学报》期刊1992年03期）
视动震颤论文开题报告
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Objectives: To measure vertical and horizontal responses to optokinetic (OK) s timulation and investigate directional abnormalities of quick phases in progress ive supranuclear palsy (PSP). Methods: Saccades and OK nystagmus were studied in six PSP patients, five with Parkinsons disease (PD), and 10 controls. The OK stimulus subtended 72°horizontally, 60°vertically, consisted of black and whit e stripes, and moved at 10-50°/s. Results: All PSP patients showed slowed volu ntary vertical saccades and nystagmus quick phases compared with PD or controls. Small, paired, horizontal saccadic intrusions (SWJ) were more frequent and larg er in PSP during fixation. Vertical saccades were transiently faster at the time of SWJ and horizontal saccades in PSP. During vertical OK nystagmus, small quic k phases were often combined with horizontal SWJ in all subjects; in PSP the vec tor was closer to horizontal. Vertical OK slow phase gain was reduced in PSP but , in most PD patients, was similar to normals. The average position of gaze shif ted in the direction of vertical OK stimulus in PSP patients with preserved slow phase responses but impaired quick phases. Conclusions: Vertical OK responses i n PSP show impaired slow phase responses, and quick phases that are slowed and c ombined with SWJ to produce an oblique vector. SWJ facilitate vertical saccades and quick phases in PSP, but it is unclear whether this is an adaptive process o r a result of the disease. A large OK stimulus is useful to induce responses tha t can be quantitatively analysed in patients with limited voluntary range of ver tical gaze.
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视动震颤论文参考文献
[1].Lopez,C,Borel,L,Magnan,J,Lacour,M.,张磊.单侧前庭功能丧失后的扭转视动性眼球震颤的非对称功能及代偿作用[J].世界核心医学期刊文摘.眼科学分册.2006
[2].Garbutt,S,,Riley,D,E.进行性核上性麻痹患者视动性眼球震颤异常[J].世界核心医学期刊文摘(神经病学分册).2005
[3].Garbutt,S,,Riley,D,E.进行性核上性麻痹所致视动性眼球震颤的异常表现[J].世界核心医学期刊文摘.眼科学分册.2005
[4].杨东生,孙复川.经直接与间接通路的视动震颤(OKN)眼动反应[J].生理学报.1998
[5].韦敏,曹洋,杨东生,孙复川.家兔视动震颤(OKN)眼动反应的方向特性[J].生物物理学报.1998
[6].曹洋,孙复川.复合运动条纹刺激下的视动震颤(OKN)眼动反应[J].生理学报.1997
[7].杨东生.视动震颤(Optokinetic Nystagmus)与双眼视功能[J].眼科研究.1997
[8].杨东生,吴冰,孙复川,李欢.正常及异常双眼视觉的视动震颤（OKN）反应特性研究[J].生物物理学报.1996
[9].韦敏,孙复川,邵殿华.运动图形刺激时家兔的视动震颤反应[J].生物物理学报.1995
[10].韦敏,孙复川.不同运动图象同时刺激左右眼时的交替视动震颤(OKN)现象[J].生物物理学报.1992